The Dr. Samuel A. Mudd House Museum in Waldorf, Maryland, preserves the historic residence of a physician whose life became inseparably intertwined with one of the most consequential events in American history. Dr. Samuel A. Mudd practiced medicine in rural Maryland during the mid-nineteenth century, serving the medical needs of the local community through house calls and office consultations typical of country physicians of his era. The doctor's modest success in his medical practice and growing family created a comfortable existence characteristic of rural professional classes in the border states during the antebellum and Civil War periods. His residence, constructed during the middle years of the nineteenth century, reflected the architectural standards and domestic arrangements of a moderately prosperous rural professional household. The house contained multiple rooms for family living, sleeping quarters, and medical consultation spaces necessary for the practice of nineteenth-century medicine. The property included surrounding land typical of rural Maryland estates, providing agricultural pursuits and outdoor spaces for family use. On the morning of April 15, 1865, the day following President Abraham Lincoln's assassination at Ford's Theatre in Washington, D.C., the fugitive John Wilkes Booth and an associate fled southward on horseback seeking escape from the immediate vicinity of the crime and attempting to reach Confederate territory or sympathetic territory where they might find refuge. During their flight, Booth sustained a fractured leg, presumed to have occurred during his jump from the theater balcony to the stage following the shooting of the president. Desperate for medical attention that might allow continued flight rather than certain capture, Booth presented himself at Dr. Mudd's residence seeking treatment for his injury. Dr. Mudd set the fractured bone, providing medical care while unaware of the true identity and circumstances of his patient, though questions remain regarding the extent of his actual knowledge of the assassination at that precise moment. The doctor provided food, shelter, and medical treatment to Booth and his associate, actions that would subsequently subject Mudd to arrest, military trial, conviction, and imprisonment on charges of conspiracy in the assassination. The Dr. Samuel A. Mudd House has become recognized as a site of historical significance due to its association with the assassination and subsequent manhunt for Lincoln's killer. The residence now operates as a museum dedicated to documenting these events and preserving the historical record of the Mudd family during this turbulent period. The museum contains period furnishings and artifacts related to the Civil War era, the assassination, and the Mudd family's experience. The paranormal phenomena reported at the museum suggest the presence of multiple spiritual entities whose origins appear connected to the historical events centered on the Mudd house. Mrs. Frankie Mudd, the doctor's wife, is believed to be the primary ghost inhabiting the residence, her spirit apparently remaining attached to the domestic space she occupied during her lifetime and the traumatic events that occurred within her home. Additional paranormal entities reported at the museum include the possible spirit of John Wilkes Booth himself, manifestations of Confederate soldiers who may have visited or occupied the property during the Civil War era, and an unidentified child spirit of unknown historical origin. Paranormal reports from visitors and staff include disembodied voices heard in various rooms, electric candles in window displays spontaneously turning on without logical explanation particularly during Civil War reenactment events held on the property, a humanoid impression appearing on beds as though an invisible person has lain down, sightings of gray-clad Confederate soldiers marching in formation around the property's well area, women's laughter and crying originating from the vicinity of the well, tugging sensations on clothing attributed to a child entity, disembodied voices repeatedly proclaiming "I'm not guilty," and faint knocking sounds at the front door believed to represent Booth's ghost. The museum currently remains closed pending spring 2026 reopening, allowing for preservation and restoration work to continue on this historically significant paranormal location.